Shared Topic: Tour of Azeroth
You won't find Locke anywhere near the hatch, because he's setup a 'sharp blades' shop in Howling Fjord. As like in the show, he's undead. Won't see him turn into the smoke monster, but he's definitely not going to be dying again soon.
On the other hand, Desmond has departed from Dalaran. He was given a great job in as a glyph vendor, but he and several of the Lost cohorts have disappeared.
Thanks for coming along on this tour. Next time, check out the Star Trek themed tour of Netherstorm.